美國PrimCells原代細胞：PrimCells的原代細胞產品采用獨特的高效提取方法， 分離，并通過盡量縮短體外培養時間從而保證其更接近體原始狀態，以適應客戶對細胞品質的嚴格要求。PrimCells亦是多種腎臟來源原代細胞的世界**供應商，為多家知名**研發企業提供**藥效與毒理測試。此外，PrimCells還開發出多種轉基因胚胎干細胞、原代胚胎成纖維細胞等產品，是干細胞與重編程領域**的報告基因原代細胞提供商。
| Species: | Sprague Dawley | Catalog Number: | PCKDR01 |
| Cell Number: | ~1x106 | Storage/Shipping: | Freshly Isolated |
Introduction:
Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.
PrimCells is proud to isolate and provide the primary cultures of podocytes from Sprague Dawley rats to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.
PrimCells是位于美國加州圣迭戈的一家專業致力于細胞產品研發和解決方案提供的業內技術領導企業。
公司匯集了**的生物醫藥技術專家，獨立開發了多項原代細胞和干細胞相關的專有技術。 公司以“細胞研究的選擇”為宗旨，自主研發超過70種**產品，填補了多個特種細胞市場的空白。例如其誘導性表達細胞庫和高效3D皮膚培養系統，皆為該類產品目前市場上少數的規模化供應商。此外，公司以高質量的數據與快速穩定的項目完成時間，長期為多家知名制藥公司提供解決方案，獲得用戶廣泛贊譽。
PrimCells產品線：
PrimCells 解決方案
1.誘導性穩定細胞株開發 2. 原代細胞開發 3. **體外毒理和效能測試 4. 3D-皮膚培養
PrimCells合作伙伴及客戶:
A．生物制藥公司：輝瑞(Pfizer), 諾華(Novartis), 禮來(Eli2 Lilly),. Amgen, EMD Millipore, Regeneron等公司的毒理和醫藥研發部門
B．科研機構：冷泉港實驗室，哈佛醫學院, 麻省理工（MIT）,， UCSF, NYU, Salk, UIUC, USC等
